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Treatment of urticaria

Treatment of urticaria

Treatment of urticaria

Treatment of urticaria

Certain investigations may be needed to identify the probable cause. C1 esterase inhibitor may be quantitatively reduced in hereditary angioedema. A skin biopsy may be helpful if urticarial vasculitis is suspected. Non-sedative antihistamines such as loratadine or dexofenadine and cetirizine are effective for one-third of patients with chronic urticaria, one-third show moderate benefits, whilst the result in the remaining third of patients are minimal. If a patient fails to respond to one of these agents after 2 weeks of therapy adding in an H2-blocker, such as cimetidine or ranitidine, may help. A number of other agents have been used, including mast cell stabilizers and leukotriene inhibitors and systemic corticosteroids. Urticaria may be caused by aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) and it is advisable to suggest alternatives such as paracetamol.

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