High-Intensity Focused Ultrasound (HIFU, or sometimes FUS for Focused Ultrasound) is an extremely precise medical procedure that applies high-intensity focused sonic energy to locally heat and destroy diseased or damaged tissue through ablation. HIFU is a hyperthermia therapy, a class of clinical therapies that use temperature to treat diseases. HIFU is also one modality of therapeutic ultrasound, involving minimally invasive or non-invasive methods to direct acoustic energy into the body.