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Treatment of sickle cell disease

Treatment of sickle cell disease

Treatment of sickle cell disease

Treatment of sickle cell disease

Consultation and assessment

Operations and procedures

Tests and investigations

All patients with sickle–cell disease should receive prophylactic daily supplements of folic acid, and penicillin V to protect against pneumococcal infection, which may be lethal in the presence of hyposplenism. These patients should be vaccinated against Pneumococcus and, where available, Haemophilus influenzae B and hepatitis B. Vaso-occlusive crises are managed by aggressive rehydration, oxygen therapy, adequate analgesia (which often requires opiates) and antibiotics. Allogeneic stem- cell transplants from HLA – matched siblings appears to be potentially curative.

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