Advertisement

Symptoms, diagnosis and causes of haematological malignancies

Symptoms, diagnosis and causes of haematological malignancies

Symptoms, diagnosis and causes of haematological malignancies

Symptoms, diagnosis and causes of haematological malignancies

Operations and procedures

Tests and investigations

Submit a request for further information, a quotation or indicative cost. Your enquiry will be forwarded to up to 3 private healthcare providers. They will respond directly with further information.

Get a quote for haematological malignancies treatment >

Leukaemias: Acute and Chronic

  • Approx 5000 adult cases per year (all types) in England and Wales
  • 75% occur in patients aged over 60 years, but all ages can be affected
  • Risk factors include previous chemotherapy/radiotherapy and exposure to radiation
  • Most cases are diagnosed following a blood count undertaken because of symptoms and/or signs of bone marrow failure (fatigue, pallor, bruising, bleeding, infections etc)
  • Some leukaemias may present with enlarged lymph glands and/or liver and spleen
  • Chronic lymphocytic leukaemia (CLL) is an indolent disease normally diagnosed on blood film, which does not usually require urgent referral

Non Hodgkin's Lymphoma

  • Approx 7000 adult cases per year in England and Wales
  • 67% of cases occur in patients aged over 60 years, but all ages can be affected
  • Presenting features include:
    • Enlarged lymph glands
    • Enlarged liver and spleen
    • Fatigue
    • Weight loss
    • Night sweats
    • 40% present with tumour outside lymph glands

Hodgkin's Disease

  • Approximately 1200 new cases per year in England and Wales
  • Over 50% of cases occur below the age of 40 years
  • Clinical features similar to those for Non-Hodgkin's lymphomas (but 95% present with lymph gland involvement)

Myeloma

  • Approximately 3000 new cases per year in England and Wales
  • 99% of cases are aged over 40 years and 95% are aged over 50 years
  • Clinical features include:
    • Bone pain +/- bone fractures
    • Symptoms of anaemia
    • Kidney problems
  • Erythrocyte sedimentation rate (ESR) or plasma viscosity may be grossly elevated

See your doctor if you have:

  • Enlarged lymph glands (> 1 cm) persisting for 6 weeks
  • Enlarged liver and spleen
  • Bone pain associated with anaemia and a raised ESR (or plasma viscosity)
  • Constellation of 3 or more of the following symptoms:
    • Fatigue
    • Night sweats
    • Weight loss
    • Itching
    • Breathlessness
    • Bruising
    • Recurrent infections
    • Bone pain

Submit a request for further information, a quotation or indicative cost. Your enquiry will be forwarded to up to 3 private healthcare providers. They will respond directly with further information.

Get a quote for haematological malignancies treatment >

Advertisement

Features

Latest news

Ewen Griffiths in the spotlight

Covid 19 services at The London General Practice

Andrew Goldberg was featured on Radio 4's 'Inside Health'.

Symptoms, diagnosis and causes of haematological malignancies

Find a ...

Advertisement