XIAPEX® is a non-surgical treatment for Dupuytren’s contracture for adults with a stiffening of the rope-like cord that pulls the fingers towards the wrist. XIAPEX® consists of enzymes called collagenases, which break down this cord allowing the fingers to extend as near to straight as possible again. A small amount of Xiapex is placed in the diseased tissue via a needle. The hand is dressed and the patient must not attempt to straighten their fingers themselves. After 24 hours, the finger is anaesthetised and gently manipulated into a straight position. The wound is inspected within one week and a lightweight thermoplastic splint is fashioned by the hand therapist. Hand therapy begins immediately and patients are encouraged to regain full activity as soon as one week post procedure.