A Harley Street heart specialist with extensive experience in all aspects of adult cardiology. Particular interests include the management of ischaemic heart disease, the role of revascularisation by percutaneous coronary intervention and coronary artery bypass surgery, the investigation and treatment of hypertension, the management of heart failure, the investigation of palpitations, dizzy spells and blackouts, and cardiac risk factor assessment.
Education and training
Dr. Holdright graduated from UCL and UCH, London, in 1984. Her specialist postgraduate training in cardiology was undertaken at The National Heart Hospital, The Royal Brompton Hospital, The London Chest Hospital and UCL Hospitals, London. During her training, Dr. Holdright also undertook a period of research at The National Heart & Lung Institute, London. She has over a decade’s experience as a consultant and has had her own private practice since 1997.
Expertise
Dr. Holdright's practice comprises a broad spectrum of cardiological conditions, and she specialises particularly in the management of ischaemic heart disease (angina and the prevention of heart attacks), the role of revascularisation by percutaneous coronary intervention (coronary angioplasty and stenting) and coronary artery bypass surgery, the investigation of cardiac causes of stroke, the heart:brain interface, management of valvular heart disease, and the treatment of heart failure. Diana Holdright has a particular interest in the assessment of coronary risk in individuals not known to have heart disease, but who are concerned that they may be at the risk, for example, due to a family history of heart disease, or by virtue of possessing one or more recognised risk factors for the development of heart disease. She is a strong advocate of coronary artery calcium scoring to refine cardiac risk.
Dr. Holdright was instrumental in establishing primary angioplasty for the acute management of myocardial infarction (heart attack) at The Heart Hospital in central London. This is one of the recognised Heart Attack Centres in London, providing 24 hour emergency angioplasty (PCI) for patients with acute myocardial infarction in the Greater London area.
Dr. Holdright is also cardiologist to the National Hospital for Neurology and Neurosurgery, where she troubleshoots the heart:brain interface. This is a unique position that has given her considerable experience in the management of dizzy spells and blackouts, the assessment of cardiac risk in epilepsy, the investigation and management of cardiac causes of stroke, the effect of neurological and neuromuscular problems on the heart, and the assessment of the cardiac contribution to autonomic dysfunction.
Dr. Holdright served on Secretary of State for Transport’s Honorary Medical Advisory Panel on Driving and Disorders of the Cardiovascular System for 10 years.
Professional activities
Publications
Dr. Holdright has published extensively; she has more than 100 peer-reviewed articles, invited articles and abstracts in print. She has also contributed chapters and had 5 books published, both individually and in collaboration with others. Key titles include:
Peer-reviewed
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Ludman A, Yellon D, Hasleton J, Ariti C, Babu GG, Boston-Griffiths E, Venugopal V, Walker M, Holdright DR, Swanton H, Crake T, Brull D, Moon J, Puranik R, Mutharangu V, Taylor, Hausenloy J. Effect of erythropoietin as an adjunct to primary percutaneous coronary intervention: a randomised controlled clinical trial Heart 2011;97:1560-1565.
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Rugg-Gunn FJ, Holdright DR
Epilepsy and the heart
BJC 2010;17:223-9
- Gray MA, Taggart P, Sutton PM, Groves D, Holdright DR, Bradbury D, Brull D, Critchley HD.
A cortical potential reflecting cardiac function.
PNAS published April 9 2007.10.1073/pnas.0609509104
- Critchley HD, Taggart P, Sutton PM, Holdright DR, Batchvarov V, Hnatkova K, Malik M, Dolan RJ.
Mental stress and sudden cardiac death: asymmetric midbrain activity as a linking mechanism.
Brain 2005;128:75-85
- Rugg-Gunn FJ, Simister RJ, Squirrell M, Holdright DR, Duncan JS.
Cardiac arrhythmias in focal epilepsy: a prospective long-term study.
Lancet 2004;364:2212-2219.
Books
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Tutorials in Differential Diagnosis
Beck ER, Souhami RL, Hanna MG, Holdright DR
Churchill Livingstone (revised 2003)
Book chapters
Teaching and training
Dr. Holdright was previously the Educational Supervisor in Cardiology to UCLH and played an active role in teaching and training, lecturing, examining and working with a wide range of clinicians across all specialties, both at undergraduate and postgraduate level.
Research
Dr. Holdright has undertaken wide-ranging research spanning nearly three decades, encompassing her many areas of clinical interest which, in more recent years, has focussed on the heart:brain interface and myocardial ischaemia.
Where can I get treatment?
NHS practice
Dr. Holdright is a Consultant Cardiologist at The Heart Hospital, UCLH, London. UCLH (UCL Hospitals) also incorporates University College Hospital & The National Hospital for Neurology.
Private practice
Dr. Holdright's private cardiology practice is based in Central London. She sees outpatients in her consulting rooms at 110 Harley Street, where she can be contacted by phone, email, fax, or in writing.
Dr. Holdright has a modern and welcoming practice, which prides itself on a personal approach to patient care. At her consulting rooms she offers a complete range of outpatient cardiac services; a cardiac physiologist is on hand to carry out diagnostic and routine cardiac investigations including ECGs, echocardiograms and 24 hour ECG and blood pressure monitor fittings. Dr. Holdright’s practice is located in the heart of London’s medical district and as such the state of the art facilities required for any additional investigations are just a few steps away.
Private patients requiring hospital admission for investigation and treatment are generally admitted to The Harley Street Clinic, London. Dr. Holdright also has admitting rights to King Edward VII Hospital for Officers and The London Clinic, both also in Central London.
UK residents wishing to see Dr. Holdright at her private practice should request a referral letter from their GP or specialist.
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