| Test |
Fluid |
Normal Range* |
Turn around time* |
Indications |
| Alpha-1-Antitrypsin |
Serum |
1.4 - 3.4 g/L |
24hrs |
Perinatal Jaundice Juvenile Cirrhosis Centrilobular Emphysema |
| Alpha-1-Antitrypsin |
Faeces |
<5 mg/g |
up to 5 days |
Protein-losing enteropathy |
| Alpha-1-Antitrypsin |
Serum |
MM pattern |
up to 5 days |
Indicated where levels are <1g/L |
| Phenotyping |
| Alpha-feto-protein |
Serum |
<20 mg/L |
up to 5 days |
Diagnosis and monitoring of Hepatoma/Teratoma |
| Alpha-feto-protein |
Amniotic Fluid |
5-25 mg/L (depends on gestational age) |
72 hrs |
Pre-natal screening for neural tube defects/chromosomal abnormalities |
| Beta-2-Microglobulin |
Serum |
<4 mg/L |
up to 5 days |
HIV infection Myeloma and lymphoreticular malignancy monitoring |
| Bence-Jones Protein |
Urine |
Negative |
up to 5 days |
Multiple Myeloma |
| Complement |
| C3 |
Serum |
0.75 - 1.5 g/L |
24 hrs |
Renal Disease, SLE, Immune complex disease, vasculitis, angioedema |
| C4 |
Serum |
0.15 - 0.54 g/L |
| C1 esterase inhibitor |
Serum |
0.18 - 0.28 g/L |
24 hrs |
Hereditary angioedema |
| CH50 |
Serum |
4 - 40 units/mL |
up to 5 days |
Hereditary complement deficiencies, recurrent meningitis, familial SLE |
| C3 Nephritic |
Serum |
Negative |
up to 5 days |
Mesangiocapillary GN Type II |
| C3 Degradation Products |
Serum |
Negative |
up to 5 days |
Complement consuming states eg, SLE |
| Other complement tests on discussion with lab up to 5 days |
| C-reactive protein |
Serum |
<4 mg/L |
24 hrs |
Infection, inflammation tissue injury malignancy |
| Cryoglobulins |
|
Negative |
48 hrs |
Cold-included Skin/joint/renal disease |
| IgG/Total ratio |
CSF |
< 11% |
up to 5 days |
Demyelinating protein conditions, eg, MS |
| CSF Isoelectric focussing for oligocentral bands |
CSF |
Negative |
up to 5 days |
Demyelinating conditions, eg, MS Other inflammatory states, eg, SLE, neurosarcoid |
Electrophoresis/ IEP/Immunfix'n |
Serum |
|