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Apigenin found to improve cancer treatment efficacy

Apigenin found to improve cancer treatment efficacy
Ingesting apigenin can enhance the ability of cancer cells to respond to cancer treatment, it has been revealed.

According to scientists at the University of Riverside, apigenin is instrumental in the isolation of the tumour suppressor p53.

This process ensures that cancer cells can be killed and chemotherapy is effective.

"In therapy you want to kill cancer cells," Xin Cai, first author of the research paper, commented.

"But to stop cell growth and to kill the cell, p53 first needs to be moved to the cell's nucleus to function. Apigenin is very effective in localising p53 this way."

It is hoped that the finding, the details of which appear in the Proceedings of the National Academy of Sciences, will act to reduce the risk of tumour resistance hindering chemotherapy treatment.

Apigenin is commonly found in fruits and vegetables including grapes, apples and artichokes.

Department of Health guidelines stress that people should eat at least five portions of fruit or vegetables every day.

© Adfero Ltd


Cancer news : 28//10/2008