Hormone therapy can 'reduce heart failure risk'

Oestrogen treatment in people with a rare circulatory condition may prevent them from suffering heart failure, a new study has found.

Pulmonary hypertension stops the pulmonary arteries from stretching, meaning the heart has to work harder to push blood to the lungs where it can be oxygenated and the Pulmonary Hypertension Association says the disease should not be confused with regular high blood pressure.

Scientists at University of California, Los Angeles were able to use oestrogen to reverse the effects of the disease, restoring full circulatory function to the affected blood vessels.

Professor Mansoureh Eghbali said: "Oestrogen appears to work through an interplay of several factors, including suppression of lung inflammation and fibrosis, as well as reversal of ventricle enlargement."

She added that it is likely a genetic mutation that affects oestrogen activity across cell boundaries is leading to the disease as the majority of cases of pulmonary hypertension are seen in young females – an age group that should be producing enough natural oestrogen. 

Comment on this page »


Latest news

Chelsea and Westminster named the best place to work in the NHS for 2015

Nuffield Health opens doors of new Cambridge Hospital

Nuffield Health plans to open state-of-the-art diagnostic suite

Hormone therapy can 'reduce heart failure risk'
Connect with us on:

This site compiles with the HONcode standard for trustworthy health information