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New cancer treatment target discovered

Vall d'Hebron University Hospital
Doctors believe they may have found a new protein which could be a promising target for cancer treatment drugs in the future.

A team of scientists from the Vall d'Hebron Institute of Oncology in Barcelona looked at the biological processes involved in the formation of glioblastoma - the most common variety of brain tumours and one of the most aggressive forms of all cancers.

They discovered that the USP15 protein is the one that initiates a chemical pathway that makes the tumour unrecognisable to the body's inherit immune system and thus allows it to grow.

Lead researcher Dr Joan Seoane explained "When we inhibited USP15 in a real model of human glioblastoma, [chemical pathway] activity decreased and the tumour did not develop. USP15 regulates tumour progression and is critical in cancer."

The doctors added that the USP15 protein could also be responsible for a number of other types of cancer including ovarian and breast.

© Adfero Ltd


Cancer treatment news : 21 February 2012