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Cancer treatment could use new drug combinations

Mayo Clinic logo

Ovarian cancer treatment could soon utilise a new combination of drugs.

Researchers at Mayo Clinic observed the usage of the medicines and their effects on cancer cells which have resisted conventional treatment methods.

Doctors explained that the findings could be important because many deaths attributed to ovarian cancer occur when the current drugs become ineffective.

In this new study, ixabepilone and sunitinib were found to activate the RhoB - a molecule known as a significant factor to drug effectiveness in other cancer variants.

"We find that with this combination of drugs, RhoB is increased and cells die," said the study's senior investigator John Copland.

He believes that the concentration of the molecule could also help doctors identify which patients would benefit most from the drug combination.

According to Cancer Research UK, women over the age of 50 are more likely to be affected by the disease, which is the second most common gynaecological cancer.

© Adfero Ltd


Cancer treatment news : 10 December 2011