Side effects from drugs used to treat infertility tend to be minor, although some patients have reported mood changes, tiredness and muscle aching. Rarely, allergic reactions have been reported. In less than 5% of women, a condition called Ovarian Hyperstimulation Syndrome (OHSS) can occur when using drugs for ovarian stimulation. OHSS is most commonly seen in younger women and those with polycystic ovaries. Symptoms include lower abdominal pain and swelling, nausea or vomiting. Women at risk of developing OHSS must stop drugs whilst continuing with GnRG analogue. Egg collection is arranged when oestrogen drops to an appropriate level or, alternatively, the cycle may be cancelled. The clinic must be contacted immediately for any symptom, however mild.
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