| Spire Alexandra Hospital | Chatham | Kent | ME5 9PG |
| Spire Barnsley Consulting Rooms | Barnsley | West Yorkshire | S70 2JT |
| Spire Bristol Hospital | Bristol | Avon | BS6 6UT |
| Spire Bushey Hospital | Bushey, Watford | Hertfordshire | WD23 1RD |
| Spire Cambridge Lea Hospital | Cambridge | Cambridgeshire | CB24 9EL |
| Spire Cardiff Hospital | Cardiff | South Glamorgan | CF23 8XL |
| Spire Cheshire Hospital | Warrington | Cheshire | WA4 4LU |
| Spire Clare Park Hospital | Farnham | Surrey | GU10 5XX |
| Spire Dunedin Hospital | Reading | Berkshire | RG1 6NB |
| Spire Elland Hospital | Elland | West Yorkshire | HX5 9EB |
| Spire Fylde Coast Hospital | Blackpool | Lancashire | FY3 8BP |
| Spire Gatwick Park Hospital | Horley | Surrey | RH6 0BB |
| Spire Harpenden Hospital | Harpenden | Hertfordshire | AL5 4BP |
| Spire Hartswood Hospital | Brentwood | Essex | CM13 3LE |
| Spire Hull and East Riding Hospital | Hull | East Yorkshire | HU10 7AZ |
| Spire Leeds Hospital | Leeds | West Yorkshire | LS8 1NT |
| Spire Leicester Hospital | Leicester | Leicestershire | LE2 2FF |
| Spire Little Aston Hospital | Sutton Coldfield | West Midlands | B74 3UP |
| Spire Liverpool Hospital | Liverpool | Merseyside | L18 1HQ |
| Spire Manchester Hospital | Manchester | Greater Manchester | M16 8AJ |
| Spire Methley Park Hospital | Leeds | West Yorkshire | LS26 9HG |
| Spire Murrayfield Hospital, Edinburgh | Edinburgh | | EH12 6UD |
| Spire Murrayfield Hospital, Wirral | Wirral | Merseyside | CH61 1AU |
| Spire Norwich Hospital | Norwich | Norfolk | NR4 7TD |
| Spire Parkway Hospital | Solihull | West Midlands | B91 2PP |
| Spire Portsmouth Hospital | Havant | Hampshire | PO9 5NP |
| Spire Regency Hospital | Macclesfield | Cheshire | SK11 8DW |
| Spire Roding Hospital | Redbridge | Essex | IG4 5PZ |
| Spire Shawfair Park Hospital | Edinburgh | | EH22 1FE |
| Spire South Bank Hospital | Worcester | Worcestershire | WR5 3YB |
| Spire Southampton Hospital | Southampton | Hampshire | SO16 6UY |
| Spire St Saviours Hospital | Hythe | Kent | CT21 5AW |
| Spire Sussex Hospital | St. Leonards-on-Sea | East Sussex | TN37 7RE |
| Spire Thames Valley Hospital | Slough | Buckinghamshire | SL3 6NH |
| Spire Tunbridge Wells Hospital | Tunbridge Wells | Kent | TN3 ORD |
| Spire Washington Hospital | Washington | Tyne & Wear | NE38 9JZ |
| Spire Wellesley Hospital | Southend On Sea | Essex | SS2 4XH |
